With particularly important geostrategic value, the Greater Mekong Sub-region is increasingly attracting the attention of major countries.

Along with the potential and available advantages, the presence of major countries in the Sub-region is an opportunity to promote bilateral and multilateral cooperation through mechanisms and initiatives, notably the initiative. East-West Economic Corridor (EWEC). With the process of formation, development and implementation in the field, EWEC contributes to promoting economic growth, sustainable development, hunger eradication, poverty reduction, and improvement of people's living standards in the lower Mekong region. 

The Mekong sub-region is located among the most dynamic and developed economic regions of Asia today in terms of trade, investment and infrastructure development. The sub-region plays an increasingly important role as a "bridge" between the two emerging economies in Asia, namely China, India and the member countries of the Association of Southeast Asian Nations (ASEAN); At the same time, it is also a trade corridor from Japan, China to India, West Asia and the Mediterranean. Therefore, the Sub-region has strategic values ​​and special interests that are important not only to countries in Southeast Asia but also to countries outside the region. With such geo-political, economic and security values, the Mekong Sub-region occupies an important position in the relationship between regions in the world; At the same time, it is the basis for the goal of interest, engagement and influence of major countries in Southeast Asia, especially China and the US - both countries want to increase and expand trade. and invest directly in this area.